DR3 / TNFRSF25 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-865-0.1mg | 0.1mg | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
TNFRSF25,DR3,APO3,DDR3,TNFRSF12,WSL,WSL1
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo-3, Death receptor 3 (DDR3 or DR3), Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor TRAMP, Lymphocyte-associated receptor of death, Apo-3, which is a member of the TNF-receptor superfamily. TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK.
Background References:
- Kitson J., et al., 1996, Nature 384:372-375.
- Bodmer J.-L., et al., 1997, Immunity 6:79-88.
- Marsters S.A., et al., 1996, Curr. Biol. 6:1669-1676.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
Fc Tag
NCBI Gene ID #:
8718
NCBI Official Name:
Tumor necrosis factor receptor superfamily, member 25
NCBI Official Symbol:
DR3 / TNFRSF25
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
45.5 kDa
Protein Accession #:
AAI17190
Purity:
>95% as determined by SDS-PAGE.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q93038