IgG Fc Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-892-0.2mg | 0.2mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
IgG Fc
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
Background References:
- Medinger M, Tzankov A,et al.(2010), J Clin Immunol. 30 Suppl 1:S9-14.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
His Tag
NCBI Gene ID #:
3500
NCBI Official Name:
Immunoglobulin heavy constant gamma 1
NCBI Official Symbol:
IgG Fc
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
27 kDa
Protein Accession #:
P01857
Purity:
>95% as determined by SDS-PAGE.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P01857