Cefpodoxime

Chemodex
Product Code: CDX-C0361
Supplier: Chemodex
CodeSizePrice
CDX-C0361-M02525 mg£53.00
Quantity:
CDX-C0361-M100100 mg£151.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
Ambient

Images

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Chemical Structure

Chemical Structure

Further Information

Alternate Names/Synonyms:
R 3763; (6R,7R)-7-{2-(2-Amino-4-thiazolyl)-2-[(Z)-methoxy-imino]acetamido}-3-(methoxymethyl)-3-cephem-4-carboxylate
Appearance:
White to off-white powder.
CAS:
80210-62-4
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS08
Handling Advice:
Protect from light and moisture.
Hazards:
H317, H334
InChi:
InChI=1S/C15H17N5O6S2/c1-25-3-6-4-27-13-9(12(22)20(13)10(6)14(23)24)18-11(21)8(19-26-2)7-5-28-15(16)17-7/h5,9,13H,3-4H2,1-2H3,(H2,16,17)(H,18,21)(H,23,24)/b19-8+/t9-,13-/m1/s1
InChiKey:
WYUSVOMTXWRGEK-LMCFTXQDSA-N
Long Description:
Chemical. CAS: 80210-62-4. Formula: C15H17N5O6S2. MW: 427.46. Synthetic. Cefpodoxime is a metabolite of cefpodoxime proxetil, an oral third generation cephalosporin antibiotic. It is active against most Gram positive and Gram negative bacteria (MIC90 ranges from 0.015-8 µg/ml). It is commonly used to treat acute otitis media, pharyngitis, and sinusitis. Cefpodoxime inhibits cell wall synthesis by inhibiting the final transpeptidation step of peptidoglycan synthesis in cell walls.
MDL:
MFCD00864906
Molecular Formula:
C15H17N5O6S2
Molecular Weight:
427.46
Package Type:
Vial
Precautions:
P261, P280, P342+P311
Product Description:
Cefpodoxime is a metabolite of cefpodoxime proxetil, an oral third generation cephalosporin antibiotic. It is active against most Gram positive and Gram negative bacteria (MIC90 ranges from 0.015-8 µg/ml). It is commonly used to treat acute otitis media, pharyngitis, and sinusitis. Cefpodoxime inhibits cell wall synthesis by inhibiting the final transpeptidation step of peptidoglycan synthesis in cell walls.
Purity:
>98%
Signal word:
Warning
SMILES:
O=C1[C@@H](NC(/C(C2=CSC(N)=N2)=N/OC)=O)[C@]3([H])N1C(C(O)=O)=C(COC)CS3
Solubility Chemicals:
Soluble in DMSO, ethanol or methanol (all 10mg/ml).
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

(1) K. Fujimoto, et al.; J. Antibiot. 40, 370 (1987) | (2) Y. Utsui, et al.; Antimicrob. Agents Chemother. 31, 1085 (1987) | (3) P. Angehrn, et al.; Antimicrob. Agents Chemother. 36, 2825 (1992) | (4) J.E. Frampton, et al.; Drugs 44, 889 (1992) (Review) | (5) E.C. Chocas, et al.; Ann. Pharmacother. 27, 1369 (1993) (Review)

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