NBD-X SE

NBD-X succinimidyl ester; NBD-C6 SE; 6-(7-Nitrobenzofurazan-4-ylamino)hexanoic acid NHS ester

Orange powder.

145195-58-0

32160000

solid

Protect from light and moisture.

InChI=1S/C16H17N5O7/c22-12-7-8-13(23)20(12)27-14(24)4-2-1-3-9-17-10-5-6-11(21(25)26)16-15(10)18-28-19-16/h5-6,17H,1-4,7-9H2

ULIVORQJLJKPHQ-UHFFFAOYSA-N

Chemical. CAS: 145195-58-0. Formula: C16H17N5O7. MW: 391.33. Synthetic. NBD-X, SE is an excellent amino-reactive building block that can be used to prepare peptide conjugates and other bioconjugates/biopolymers. It has much higher conjugation efficiency than NBD-Cl and NBD-F. This amine-reactive NBD derivative, containing a convenient succinimidyl ester, can be used to develop environmentally sensitive bioconjugates. NBD is a functional analog of the dinitrophenyl hapten, and its fluorescence is quenched upon binding to anti-dinitrophenyl (anti-DNP) antibodies. The X-spacer separates the fluorescent dye from the protein allowing greater sensitivity and reduced perturbation effects on protein labeling. Spectral properties: lamdaEx=460; lambdaEm=540.

MFCD00467955

C16H17N5O7

391.33

Vial

NBD-X, SE is an excellent amino-reactive building block that can be used to prepare peptide conjugates and other bioconjugates/biopolymers. It has much higher conjugation efficiency than NBD-Cl and NBD-F. This amine-reactive NBD derivative, containing a convenient succinimidyl ester, can be used to develop environmentally sensitive bioconjugates. NBD is a functional analog of the dinitrophenyl hapten, and its fluorescence is quenched upon binding to anti-dinitrophenyl (anti-DNP) antibodies. The X-spacer separates the fluorescent dye from the protein allowing greater sensitivity and reduced perturbation effects on protein labeling. Spectral properties: lamdaEx=460; lambdaEm=540.

>98% (HPLC)

O=C(ON1C(CCC1=O)=O)CCCCCNC2=CC=C([N+]([O-])=O)C3=NON=C32

Soluble in DMSO or DMF.

Synthetic.

Non-hazardous

Fluorescent Reagents

41105331

Stable for at least 2 years after receipt when stored at -20°C.