AdipoGen Life Sciences

BE-31405

Product Code:
 
AG-CN2-0302
Regulatory Status:
 
RUO
Shipping:
 
AMBIENT
Storage:
 
-20°C
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Chemical Structure
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Chemical Structure

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AG-CN2-0302-M0011 mg£270.00
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Further Information

Appearance:
White to off-white powder.
CAS:
158054-02-5
EClass:
32160000
Form (Short):
solid
Handling Advice:
Keep cool and dry.Protect from light.Protect from light when in solution.
InChi:
InChI=1S/C28H36O10/c1-12(2)18-7-15-8-25(10-29)17-6-5-13(3)16(17)9-26(15,27(18,25)24(32)33)11-34-28-22(31)20-19(35-14(4)30)21(37-28)23(36-20)38-28/h7,10,12-13,15-17,19-23,31H,5-6,8-9,11H2,1-4H3,(H,32,33)/t13-,15+,16-,17-,19-,20+,21+,22+,23+,25?,26+,27+,28-/m1/s1
InChiKey:
ULHRLJDDVCQHQE-IXWUSAGWSA-N
Long Description:
Chemical. CAS: 158054-02-5. Formula: C28H36O10. MW: 532.6. Isolated from Penicillum minioluyeum. Broad spectrum antifungal agent compared to sordarin. Shows growth inhibitory activity against pathogenic fungal strains such as Candida albicans, Candida glabrata and Cryptococcus neoformans. Inhibits the protein synthesis in Candida albicans, but not mammalian cells, most probably through elongation factor inhibition.
MDL:
N/A
Molecular Formula:
C28H36O10
Molecular Weight:
532.6
Package Type:
Vial
Product Description:
Broad spectrum antifungal agent compared to sordarin. Shows growth inhibitory activity against pathogenic fungal strains such as Candida albicans, C. glabrata and Cryptococcus neoformans. Inhibits the protein synthesis in C. albicans, but not mammalian cells, most probably through elongation factor inhibition.
Purity:
>98% (HPLC)
SMILES:
C[C@H](CC1)[C@]2([H])[C@]1([H])[C@]3(C=O)[C@](C(C(C)C)=C4)(C(O)=O)[C@]([C@@H]4C3)(CO[C@@]5(O6)O[C@]7([H])[C@@]6([H])O[C@H]([C@@H]5O)[C@H]7OC(C)=O)C2
Solubility Chemicals:
Soluble in DMSO.
Source / Host:
Isolated from Penicillum minioluyeum.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

BE-31405, a new antifungal antibiotic produced by Penicillium minioluteum. I. Description of producing organism, fermentation, isolation, physico-chemical and biological properties: H. Okada, et al.; J. Antibiot. 51, 1081 (1998) | Induced production of BE-31405 by co-culturing of Talaromyces siamensis FKA-61 with a variety of fungal strains: K. Nonaka, et al.; J. Antibiot. 68, 573 (2015)