Rifamycin AF-EPTAPI

AdipoGen Life Sciences
Product Code: AG-CN2-0326
CodeSizePrice
AG-CN2-0326-M01010 mg£120.00
Quantity:
AG-CN2-0326-M05050 mg£450.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
-20°C

Images

1 / 1
Chemical Structure

Chemical Structure

Further Information

Alternate Names/Synonyms:
Rifamycin AF/EPTAPI; 3-[[(4-Heptyl-1-piperazinyl)imino]methyl]-rifamycin
Appearance:
Red powder.
CAS:
41971-22-6
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Keep cool and dry.Protect from light.Protect from light when in solution.
InChi:
InChI=1S/C49H70N4O12/c1-11-12-13-14-15-20-52-21-23-53(24-22-52)50-26-34-39-44(59)37-36(43(34)58)38-46(32(7)42(37)57)65-49(9,47(38)60)63-25-19-35(62-10)29(4)45(64-33(8)54)31(6)41(56)30(5)40(55)27(2)17-16-18-28(3)48(61)51-39/h16-19,25-27,29-31,35,40-41,45,55-59H,11-15,20-24H2,1-10H3,(H,51,61)/b17-16+,25-19+,28-18-,50-26+/t27-,29+,30+,31+,35?,40-,41+,45+,49-/m0/s1
InChiKey:
XLFXMDIMYQHPNA-HJYHSKLVSA-N
Long Description:
Chemical. CAS: 41971-22-6. Formula: C49H70N4O12. MW: 907.1. Semisynthetic. Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex (MAC) infections.
Molecular Formula:
C49H70N4O12
Molecular Weight:
907.1
Package Type:
Vial
Product Description:
Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections.
Purity:
>98% (HPLC)
SMILES:
OC1=C(NC(/C(C)=CC=C[C@H](C)[C@H](O)[C@@H](C)[C@H]([C@@H](C)[C@@H]([C@H](C)[C@H](/C=C/O2)OC)OC(C)=O)O)=O)C(/C=N/N3CCN(CCCCCCC)CC3)=C(O)C4=C5C(O[C@@]2(C)C5=O)=C(C)C(O)=C41
Solubility Chemicals:
Soluble in DMSO, aqueous acetonitrile or ethanol.
Source / Host:
Semisynthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

Structure-Activity Relationships and DNA Polymerases From Normal and Specificity of Inhibition of Leukemia Cells of Man and From Simian Sarcoma Virus by Rifamycin Derivatives: R.A. CiCioccio & B.I.S. Srivastava; J. Natl. Cancer Inst. 61, 1187 (1978)

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