Further Information
Alternate Names/Synonyms:
Rifamycin AF/DA; 3-Formyl-25-desacetylrifamycin; 25-O-Deacetyl-3-formylrifamycin SV; NSC 145635
Red powder.
16783-97-4
32160000
liquid
Keep cool and dry.Protect from light.Protect from light when in solution.
InChI=1S/C36H45NO12/c1-15-10-9-11-16(2)35(46)37-26-21(14-38)31(43)23-24(32(26)44)30(42)20(6)33-25(23)34(45)36(7,49-33)48-13-12-22(47-8)17(3)28(40)19(5)29(41)18(4)27(15)39/h9-15,17-19,22,27-29,39-44H,1-8H3,(H,37,46)/b10-9+,13-12+,16-11-/t15-,17+,18+,19-,22?,27-,28+,29+,36-/m0/s1
GGZYOFVKHSKDIP-KUJRJRTCSA-N
Chemical. CAS: 16783-97-4. Formula: C36H45NO12. MW: 683.7. Semisynthetic. Ansamycin antibiotic. Intermediate of rifampicin. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex (MAC) infections.
MFCD12031373
C36H45NO12
683.7
Vial
Ansamycin antibiotic. Intermediate of rifampicin. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria. Therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections.
>90% (HPLC)
OC1=C(NC(/C(C)=CC=C[C@H](C)[C@H](O)[C@@H](C)[C@H]([C@@H](C)[C@@H]([C@H](C)[C@H](/C=C/O2)OC)O)O)=O)C(C([H])=O)=C(O)C3=C4C(O[C@@]2(C)C4=O)=C(C)C(O)=C31
Soluble in DMSO, aqueous acetonitrile or ethanol.
Semisynthetic.
Non-hazardous
Natural Products/Extracts
12352200
Stable for at least 2 years after receipt when stored at -20°C.