AdipoGen Life Sciences

Rifamycin AF-DA

Product Code:
 
AG-CN2-0328
Regulatory Status:
 
RUO
Shipping:
 
AMBIENT
Storage:
 
-20°C
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Chemical Structure

Chemical Structure

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AG-CN2-0328-M01010 mg£120.00
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AG-CN2-0328-M05050 mg£450.00
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
Rifamycin AF/DA; 3-Formyl-25-desacetylrifamycin; 25-O-Deacetyl-3-formylrifamycin SV; NSC 145635
Appearance:
Red powder.
CAS:
16783-97-4
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Keep cool and dry.Protect from light.Protect from light when in solution.
InChi:
InChI=1S/C36H45NO12/c1-15-10-9-11-16(2)35(46)37-26-21(14-38)31(43)23-24(32(26)44)30(42)20(6)33-25(23)34(45)36(7,49-33)48-13-12-22(47-8)17(3)28(40)19(5)29(41)18(4)27(15)39/h9-15,17-19,22,27-29,39-44H,1-8H3,(H,37,46)/b10-9+,13-12+,16-11-/t15-,17+,18+,19-,22?,27-,28+,29+,36-/m0/s1
InChiKey:
GGZYOFVKHSKDIP-KUJRJRTCSA-N
Long Description:
Chemical. CAS: 16783-97-4. Formula: C36H45NO12. MW: 683.7. Semisynthetic. Ansamycin antibiotic. Intermediate of rifampicin. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex (MAC) infections.
MDL:
MFCD12031373
Molecular Formula:
C36H45NO12
Molecular Weight:
683.7
Package Type:
Vial
Product Description:
Ansamycin antibiotic. Intermediate of rifampicin. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria. Therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections.
Purity:
>90% (HPLC)
SMILES:
OC1=C(NC(/C(C)=CC=C[C@H](C)[C@H](O)[C@@H](C)[C@H]([C@@H](C)[C@@H]([C@H](C)[C@H](/C=C/O2)OC)O)O)=O)C(C([H])=O)=C(O)C3=C4C(O[C@@]2(C)C4=O)=C(C)C(O)=C31
Solubility Chemicals:
Soluble in DMSO, aqueous acetonitrile or ethanol.
Source / Host:
Semisynthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

Rifamycins: A General View: S. Riva & L.G. Silvestri; Ann. Rev. Microbiol. 26, 199 (1972) | Rifamycin antibiotics: inhibitors of Rauscher murine leukemia virus reverse transcriptase and of purified DNA polymerases from human normal and leukemic lymphoblasts: S.S. Yang, et al.; J. Natl. Cancer Inst. 49, 7 (1972) | Rifamycin Derivatives Strongly Inhibiting RNA>DNA Polymerase (Reverse Transcriptase) of Murine Sarcoma Viruses: C. Gurgo, et al.; J. Natl. Cancer Inst. 49, 61 (1972)