Rifamycin AG
Product Code: AG-CN2-0329
Product Group: Natural Products and Extracts
Supplier: AdipoGen Life Sciences
| Code | Size | Price |
|---|
| AG-CN2-0329-M010 | 10 mg | £120.00 |
Quantity:
| AG-CN2-0329-M050 | 50 mg | £450.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
NCI 144-111; 4-[(Aminoiminomethyl)azo]-4-deoxy-rifamycin
Appearance:
Red powder.
CAS:
38128-51-7
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Keep cool and dry.Protect from light.Protect from light when in solution.
InChi:
InChI=1S/C38H49N5O11/c1-16-11-10-12-17(2)36(50)41-24-15-23(42-43-37(39)40)26-27(32(24)48)31(47)21(6)34-28(26)35(49)38(8,54-34)52-14-13-25(51-9)18(3)33(53-22(7)44)20(5)30(46)19(4)29(16)45/h10-16,18-20,25,29-30,33,45-47H,1-9H3,(H,41,50)(H4,39,40,43)/b11-10+,14-13+,17-12-,42-23+/t16-,18+,19+,20+,25?,29-,30+,33+,38-/m0/s1
InChiKey:
LGCZXXFOLXAQNH-AYTZBZETSA-N
Long Description:
Chemical. CAS: 38128-51-7. Formula: C38H49N5O11. MW: 751.8. Semisynthetic. Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex (MAC) infections.
Molecular Formula:
C38H49N5O11
Molecular Weight:
751.8
Package Type:
Vial
Product Description:
Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections.
Purity:
>98% (HPLC)
SMILES:
O=C1C(N2)=C/C(C3=C1C(O)=C(C)C(O[C@]4(C)O/C=C/[C@H](OC)[C@@H](C)[C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)/C=C/C=C(C)C2=O)=C3C4=O)=NNC(N)=N
Solubility Chemicals:
Soluble in DMSO, aqueous acetonitrile or ethanol.
Source / Host:
Semisynthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Rifamycin antibiotics: inhibitors of Rauscher murine leukemia virus reverse transcriptase and of purified DNA polymerases from human normal and leukemic lymphoblasts: S.S. Yang, et al.; J. Natl. Cancer Inst. 49, 7 (1972) | Rifamycin Derivatives Strongly Inhibiting RNA>DNA Polymerase (Reverse Transcriptase) of Murine Sarcoma Viruses: C. Gurgo, et al.; J. Natl. Cancer Inst. 49, 61 (1972) | Interaction of rifamycins with mammalian nucleic acid polymerizing enzymes: V.S. Sethi & P. Okano; Biochim. Biophys. Acta. 454, 230 (1976)
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