Tyramine
| Code | Size | Price |
|---|
| CDX-T0168-G005 | 5 g | £41.00 |
Quantity:
| CDX-T0168-G025 | 25 g | £89.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
2-(4-Hydroxyphenyl)ethylamine; 4-(2-Aminoethyl)phenol; 4-Hydroxyphenethylamine; NSC 249188; p-Tyramine; Uteramine
Appearance:
White to off-white powder.
CAS:
51-67-2
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H315-H319-H335
InChi:
InChI=1S/C8H11NO/c9-6-5-7-1-3-8(10)4-2-7/h1-4,10H,5-6,9H2
InChiKey:
DZGWFCGJZKJUFP-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 51-67-2. Formula: C8H11NO. MW: 137.2. Synthetic. Tyramine is a naturally-occurring trace amine derived from the amino acid tyrosine that is produced endogenously or can be obtained from certain foods. Tyramine acts as a catecholamine releasing agent. It is unable to cross the blood-brain barrier, resulting in only non-psychoactive peripheral sympathomimetic effects following ingestion. Acts as a adrenergic and activates trace amine-associated receptor 1. Tyramine also inhibits the release of norepinephrine and dopamine. It is metabolized by monoamine oxidase A. Primarily used as an intermediate in the manufacture of pharmaceutical and agrochemical products.
MDL:
MFCD00008193
Molecular Formula:
C8H11NO
Molecular Weight:
137.2
Package Type:
Vial
Precautions:
P261-P305 + P351 + P338
Product Description:
Tyramine is a naturally-occurring trace amine derived from the amino acid tyrosine that is produced endogenously or can be obtained from certain foods. Tyramine acts as a catecholamine releasing agent. It is unable to cross the blood-brain barrier, resulting in only non-psychoactive peripheral sympathomimetic effects following ingestion. Acts as a adrenergic and activates trace amine-associated receptor 1. Tyramine also inhibits the release of norepinephrine and dopamine. It is metabolized by monoamine oxidase A. Primarily used as an intermediate in the manufacture of pharmaceutical and agrochemical products.
Purity:
>98% (NMR)
Signal word:
Warning
SMILES:
OC1=CC=C(CCN)C=C1
Solubility Chemicals:
Soluble in DMSO, methanol or ethanol.
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) A.J. Gross & I.W. Sizer; J. Biol. Chem. 234, 1611 (1959) | (2) F. Sjoeqvist; Proc. R. Soc. Med. 58, 967 (1965) | (3) M. Da Prada, et al.; J. Neural. Transm. Suppl. 26, 31 (1988) | (4) R.B. Rothman, et al.; Science 39, 32 (2001) | (5) R. Zucchi, et al.; Br. J. Pharmacol. 149, 967 (2006) | (6) E.A. Reese, et al.; J. Pharmacol. Exp. Therap. 321, 178 (2007) | (7) J.J. Maguire, et al.; Pharmacol. Rev. 61,1 (2009)