5(6)-TAMRA N-succinimidyl ester

Chemodex
Product Code: CDX-C0027
Supplier: Chemodex
CodeSizePrice
CDX-C0027-M02525 mg£169.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
-20°C

Images

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Chemical Structure

Chemical Structure

Further Information

Alternate Names/Synonyms:
5(6)-TAMRA SE; 5(6)-Carboxytetramethylrhodamine NHS; 5(6)-Carboxytetramethylrhodamine N-succinimidyl ester
Appearance:
Dark brown powder.
CAS:
150408-83-6246256-50-8
EClass:
32160000
Form (Short):
solid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C24H22N2O3.C6H7NO4/c1-25(2)15-9-11-19-21(13-15)29-22-14-16(26(3)4)10-12-20(22)23(19)17-7-5-6-8-18(17)24(27)28;1-4(8)11-7-5(9)2-3-6(7)10/h5-14H,1-4H3;2-3H2,1H3
InChiKey:
MCDQUPOEOXETSJ-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 150408-83-6, 246256-50-8. Formula: C29H25N3O7. MW: 527.52. Synthetic. Amine-reactive form of 5(6)-carboxytetramethylrhodamine. Conjugates yield bright, pH-insensitive orange-red fluorescence (Ex/Em: ~543/576nm i MeOH) with good photostability. Fluorophores most often used for preparing peptide, protein, nucleotide and nucleic acid conjugates or other primary amine-containing molecules. Especially also used for fluorescent antibodies and avidin derivatives used in immunochemistry.
MDL:
MFCD00077324
Molecular Formula:
C29H25N3O7
Molecular Weight:
527.52
Package Type:
Vial
Product Description:
Amine-reactive form of 5(6)-carboxytetramethylrhodamine. Conjugates yield bright, pH-insensitive orange-red fluorescence (Ex/Em: ~543/576nm i MeOH) with good photostability. Fluorophores most often used for preparing peptide, protein, nucleotide and nucleic acid conjugates or other primary amine-containing molecules. Especially also used for fluorescent antibodies and avidin derivatives used in immunochemistry.
Purity:
>90% (HPLC)
SMILES:
CN(C)C1=CC=C(C(C2=CC=CC=C2C([O-])=O)=C(C=C/3)C(O4)=CC3=[N+](C)C)C4=C1.O=C(C)ON5C(CCC5=O)=O
Solubility Chemicals:
Soluble in DMSO, DMF, acetonitrile or methanol.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

(1) E. Koller Appl. Fluoresc. Technol. 3, 20, (1991) | (2) L.D. Mayfield, D.R. Corey Bioorg. Med. Chem. Lett. 9, 14, (1999) | (3) M. Hahn, et al.; Electrophoresis 22, 2691 (2001) | (4) T.M. Hsu, et al.; Clin. Chem. 47, 1373 (2001) |(5) C. Olivier, et al.; Bioconjug. Chem 14, 430 (2003) | (6) H.Y. Li, et al.; J. Cell Biol. 160, 635 (2003) | (7) W. Erker, et al.; BBRC 324, 893 (2004)