DAF-4 DA
| Code | Size | Price |
|---|
| CDX-D0216-M001 | 1 mg | £267.00 |
Quantity:
| CDX-D0216-M005 | 5 mg | £1,036.00 |
Quantity:
| CDX-D0216-M010 | 10 mg | £1,842.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
DAF-4 diacetate; 3,4-Diamino-2',7'-dichlorofluorescein diacetate
Appearance:
Light yellow powder.
CAS:
208850-34-4 (parent compound DAF-4)
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C24H16Cl2N2O7/c1-9(29)32-21-7-19-13(4-15(21)25)24(12-6-18(28)17(27)3-11(12)23(31)35-24)14-5-16(26)22(33-10(2)30)8-20(14)34-19/h3-8H,27-28H2,1-2H3
InChiKey:
OOSGYDWTQGDKAY-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 208850-34-4 (parent compound DAF-4). Formula: C24H16Cl2N2O7. MW: 515.3. Synthetic. DAF-4 is a indicator for nitric oxide. As with other fluorescein diacetates (DAFs), the non-fluorescent DAF-4 diacetate (DAF-4 DA) is membrane permeant and is deacetylated by intracellular esterases to form DAF-4, which than can ract with NO to form the fluorescent DAF-4T. Can be used for the fluorimetric detection of nitric oxide and in fluorescence microscopy to measure real-time changes in nitric oxide levels in vivo. Spectral Data: lambdaex 505nm; lambdaem 530nm.
MDL:
MFCD31656737
Molecular Formula:
C24H16Cl2N2O7
Molecular Weight:
515.3
Package Type:
Vial
Product Description:
DAF-4 is a indicator for nitric oxide. As with other fluorescein diacetates (DAFs), the non-fluorescent DAF-4 diacetate (DAF-4 DA) is membrane permeant and is deacetylated by intracellular esterases to form DAF-4, which than can ract with NO to form the fluorescent DAF-4T. Can be used for the fluorimetric detection of nitric oxide and in fluorescence microscopy to measure real-time changes in nitric oxide levels in vivo. Spectral Data: lambdaex 505nm; lambdaem 530nm.
Purity:
>90% (HPLC)
SMILES:
ClC1=C(OC(C)=O)C=C(OC(C=C(OC(C)=O)C(Cl)=C2)=C2C34OC(C5=C4C=C(N)C(N)=C5)=O)C3=C1
Solubility Chemicals:
Soluble in chloroform or DMSO.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) H. Kojima, et al.; Anal. Chem. 70, 2446 (1998) | (2) N. Nakatsubo, et al.; FEBS Lett. 427, 263 (1998) | (3) T. Nagano; Luminescence 14, 283 (1999) (Review) | (4) T. Nagano; Proc. Jpn. Acad. Ser. B 86, 837 (2010) (Review)
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