ABI2 Antibody

NSJ Bioreagents
Product Code: NSJ-R31179
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31179-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
After reconstitution, the ABI2 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of 1) human 293T, 2) human HeLa, 3) human K562, 4) human SH-SY5Y, 5) rat brain, 6) rat PC-12 and 7) mouse brain tissue lysate with ABI2 antibody. Predicted molecular weight ~55 kDa.

Western blot testing of 1) human 293T, 2) human HeLa, 3) human K562, 4) human SH-SY5Y, 5) rat brain, 6) rat PC-12 and 7) mouse brain tissue lysate with ABI2 antibody. Predicted molecular weight ~55 kDa.

Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the ABI2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
ABL Interactor 2 is a protein that in humans is encoded by the ABI2 gene. By analysis of a YAC and a BAC, Machado et al.(2000) mapped the gene to 2q31-q33. ABI2 possesses a basic N terminus with homology to a homeodomain protein; a central serine-rich region; three PEST sequences, which are implicated in susceptibility to protein degradation; several proline-rich stretches; and an acidic C terminus with multiple phosphorylation sites and an SH3 domain. Dai and Pendergast(1995) suggested that the ABI proteins may function to coordinate the cytoplasmic and nuclear functions of the ABL1 tyrosine kinase.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the N-terminus of human ABL Interactor 2 (RFKVSTQNMKMGGLPR) was used as the immunogen for this ABI2 antibody (100% homologous in human, mouse and rat).
Limitation:
This ABI2 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
Q9NYB9