NSJ Bioreagents

ACVR2A Antibody

Product Code:
 
NSJ-R32495
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
After reconstitution, the ACVR2A antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
1 / 5
Immunofluorescent staining of FFPE rat NRK cells with ACVR2A antibody (red) and DAPI nuclear stain (blue). HIER: steam section in pH6 citrate buffer for 20 min.
2 / 5
IHC testing of FFPE human intestinal cancer tissue with ACVR2A antibody at 1ug/ml. HIER: steam sections in pH6 citrate buffer for 20 min.
3 / 5
Western blot testing of 1) rat kidney and 2) human HeLa lysate with ACVR2A antibody at 0.5ug/ml. Predicted molecular weight ~58/70-80 kDa (unmodified/glycosylated).
4 / 5
Flow cytometry testing of mouse HEPA1-6 cells with ACVR2A antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= ACVR2A antibody.
5 / 5
Flow cytometry testing of rat RH35 cells with ACVR2A antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= ACVR2A antibody.
❮❯

Immunofluorescent staining of FFPE rat NRK cells with ACVR2A antibody (red) and DAPI nuclear stain (blue). HIER: steam section in pH6 citrate buffer for 20 min.
IHC testing of FFPE human intestinal cancer tissue with ACVR2A antibody at 1ug/ml. HIER: steam sections in pH6 citrate buffer for 20 min.
Western blot testing of 1) rat kidney and 2) human HeLa lysate with ACVR2A antibody at 0.5ug/ml. Predicted molecular weight ~58/70-80 kDa (unmodified/glycosylated).
Flow cytometry testing of mouse HEPA1-6 cells with ACVR2A antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= ACVR2A antibody.
Flow cytometry testing of rat RH35 cells with ACVR2A antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= ACVR2A antibody.

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CodeSizePrice
NSJ-R32495-100ug100 ug£535.00
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This product comes from: United States.
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Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml,Immunofluorescence (FFPE): 2-4ug/ml,Flow cytometry: 1-3ug/million cells
Buffer:
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Description:
Activin receptor type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids Q421-L513 from the human protein were used as the immunogen for the ACVR2A antibody.
Limitation:
This ACVR2A antibody is available for research use only.
Localization:
Cytoplasmic, membranous
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
P27037