C5 Antibody
| Code | Size | Price |
|---|
| NSJ-R31601-100ug | 100 ug | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Rat
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
The C5 antibody can be stored at 40 to -200. After reconsititution, aliquot and store at -200. Avoid repeated freeze/thaws.
Documents
Further Information
Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
Titration of the C5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
C5a is a protein fragment released from complement component C5. The protein plays an important role in inflammatory and cell killing processes. C5 is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. C5a plays a key role in increasing migration and adherence of neutrophils and monocytes to vessel walls. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to susceptibility to liver fibrosis and to rheumatoid arthritis.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
362119
Immunogen:
Rat partial recombinant protein (AA 1-77, alpha subunit) was used as the immunogen for this C5 antibody.
Limitation:
This C5 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Rat