Calretinin Antibody

NSJ Bioreagents
Product Code: NSJ-R31661
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31661-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the Calretinin antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

1 / 4
Western blot testing of Calretinin antibody and Lane 1: rat brain; 2: mouse brain lysate. Expected size ~29KD, observed size ~37KD
2 / 4
IHC-P: Calretinin antibody testing of human intestine cancer tissue
3 / 4
IHC-P: Calretinin antibody testing of mouse brain tissue
4 / 4
IHC-P: Calretinin antibody testing of rat brain tissue

Western blot testing of Calretinin antibody and Lane 1: rat brain; 2: mouse brain lysate. Expected size ~29KD, observed size ~37KD
IHC-P: Calretinin antibody testing of human intestine cancer tissue
IHC-P: Calretinin antibody testing of mouse brain tissue
IHC-P: Calretinin antibody testing of rat brain tissue

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the Calretinin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Calretinin, also known as 29 kDa calbindin, is a vitamin D-dependent calcium-binding protein involved in calcium signaling. In humans, the protein is encoded by the CALB2 gene. This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. Calretinin is mapped to 16q22.2. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
794
Immunogen:
An amino acid sequence from the C-terminal of human Calretinin (2EMNIQQLTNYRKSVMSLAEAGKLYRKDLE) was used as the immunogen for this Calretinin antibody.
Limitation:
This Calretinin antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat