Caspase-9 Antibody
| Code | Size | Price |
|---|
| NSJ-R31745-100ug | 100 ug | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
The lyophilized Caspase-9 antibody can be stored at 40. After reconstitution, aliquot and store at -200. Avoid repeated freezing and thawing.
Documents
Further Information
Application Details :
Western blot: 0.5-1ug/ml
Application Note:
Titration of the Caspase-9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Caspase-9 is also known as MCH6 or APAF3. The CASP9 gene encodes a member of the cysteine-aspartic acid protease family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex ofCytochrome Cand the Apoptotic peptidase activating factor 1. This step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
842
Immunogen:
Human partial recombinant protein (AA 3-228) was used as the immunogen for this Caspase-9 antibody.
Limitation:
This Caspase-9 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human