Caveolin-2 Antibody

NSJ Bioreagents
Product Code: NSJ-R30617
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R30617-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the Caveolin-2 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of Caveolin-2 antibody and Lane 1: rat heart; 2: rat lung; 3: HeLa; 4: A431 cell lysate
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Western blot testing of Caveolin-2 antibody and Lane 1: HeLa; 2: SMMC-7721; 3: COLO320 cell lysate
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IHC-P: Caveolin-2 antibody testing of human lung cancer tissue
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IHC-P: Caveolin-2 antibody testing of rat heart tissue

Western blot testing of Caveolin-2 antibody and Lane 1: rat heart; 2: rat lung; 3: HeLa; 4: A431 cell lysate
Western blot testing of Caveolin-2 antibody and Lane 1: HeLa; 2: SMMC-7721; 3: COLO320 cell lysate
IHC-P: Caveolin-2 antibody testing of human lung cancer tissue
IHC-P: Caveolin-2 antibody testing of rat heart tissue

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting points. Titration of the Caveolin-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Caveolin-2 is a protein related to caveolin-1 which is derived caveolin-enriched membranes. CAV2 and CAV1 are similar in most respects and they differ in their functional interactions with heterotrimeric G proteins. Both are expressed in neuronal cells. Caveolin-2 was upregulated in response to neuronal cell injury. The CAV2 gene is mapped to 7q31.1-q31.2. The CAV1 gene contains 3 exons, while the human CAV2 gene contains 2 exons. The boundary of the last exon of both are analogous, suggesting that they arose through gene duplication. The genes encoding murine caveolin-1 and -2 are colocalized within the A2 region of mouse chromosome 6.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids 1-17 (MGLETEKADVQLFMDDD-human) were used as the immunogen for this Caveolin-2 antibody.
Limitation:
This Caveolin-2 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
P51636