CIP2A Antibody / KIAA1524

NSJ Bioreagents
Product Code: NSJ-R32285
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R32285-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
After reconstitution, the CIP2A antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of 1) mouse testis and 2) human HeLa lysate with CIP2A antibody. Routinely observed at 90 kDa.

Western blot testing of 1) mouse testis and 2) human HeLa lysate with CIP2A antibody. Routinely observed at 90 kDa.

Further Information

Application Details :
Western blot: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the CIP2A antibody should be determined by the researcher.
Description:
Protein CIP2A, also known as 'cancerous inhibitor of PP2A' and p90, is a protein that in humans is encoded by the KIAA1524 gene. It is required for the malignant cellular growth and for in vivo tumor formation. In accordance with the oncogenic role of CIP2A, overexpression promotes Ras-elicited cell growth and transforms immortalized human cells (HEK-TERVs). More recently CIP2A has been shown to regulate phosphorylation and activity of many other oncoproteins and to drive malignant cell growth and tumorigenesis in various human cancer types. Importantly, CIP2A deficient mice are viable, suggesting that targeting of oncogenic function of CIP2A would not result in serious side-effects.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids EVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIH of human KIAA1524 were used as the immunogen for the CIP2A antibody.
Limitation:
This CIP2A antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse
Uniprot #:
Q8TCG1