Claudin 2 Antibody

NSJ Bioreagents
Product Code: NSJ-R30144
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R30144-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the Claudin 2 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of Claudin 2 antibody and Lane 1: rat kidney; 2: rat liver~
2 / 2
IHC-P: Claudin 2 antibody testing of human intestinal cancer tissue

Western blot testing of Claudin 2 antibody and Lane 1: rat kidney; 2: rat liver~
IHC-P: Claudin 2 antibody testing of human intestinal cancer tissue

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting points. Titration of the Claudin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Claudin 2 is a protein that in humans is encoded by the CLDN2 gene. By genomic sequence analysis, this gene is mapped to chromosome Xq22.3-q23. This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. By expression in a human intestinal epithelial cell line, it was determined that the intestine-specific homeodomain proteins CDX1 and CDX2 activated a reporter plasmid driven by the CLDN2 promoter.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
9075
Immunogen:
Human partial recombinant protein (AA 38-230) was used as the immunogen for this Claudin 2 antibody.
Limitation:
This Claudin 2 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Rat