Claudin 5 Antibody

NSJ Bioreagents
Product Code: NSJ-R30145
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R30145-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Rat
Application: Western Blot (WB)
Storage:
After reconstitution, the Claudin 5 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of Claudin-5 antibody and rat liver

Western blot testing of Claudin-5 antibody and rat liver

Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting points. Titration of the Claudin 5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Claudin-5, also known as BEC1, is a protein that in humans is encoded by the CLDN5 gene. By use of yeast artificial chromosomes, Claudin-5 is localized between polymorphic markers D22S944 and D22S941 on chromosome 22q11, both of which are deleted in more than 80% of VCFS patients. This gene encodes a member of the claudin family. Family members are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Additionally, it plays a major role in tight junction-specific obliteration of the intercellular space.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
7122
Immunogen:
Amino acids 191-218 (RPDLSFPVKYSAPRRPTATGDYDKKNYV-human) were used as the immunogen for the Claudin-5 antibody.
Limitation:
This Claudin 5 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Rat