CNTF Antibody

NSJ Bioreagents
Product Code: NSJ-R31496
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31496-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
The lyophilized CNTF antibody can be stored at 40 to -200. After reconstitution, aliquot and store at -200. Avoid repeated freeze/thaws.

Images

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Western blot testing of CNTF antibody and rat samples 1: PC12; 2: NRK; 3: RH35; 4: brain; 5: liver; 6: spleen; 7: testis lysate. Expected/observed size ~23KD
2 / 3
IHC-P: CNTF antibody testing of rat brain tissue
3 / 3
IHC-P: CNTF antibody testing of mouse brain tissue

Western blot testing of CNTF antibody and rat samples 1: PC12; 2: NRK; 3: RH35; 4: brain; 5: liver; 6: spleen; 7: testis lysate. Expected/observed size ~23KD
IHC-P: CNTF antibody testing of rat brain tissue
IHC-P: CNTF antibody testing of mouse brain tissue

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,ELISA: 0.1-0.5ug/ml
Application Note:
Titration of the CNTF antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Ciliary neurotrophic factor is a protein that in humans is encoded by the CNTF gene. The protein encoded by this gene is a polypeptide hormone andnerve growth factor whose actions have mainly been studied in the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neural populations includingastrocytes. It is mapped to 11q12.1. In addition to neurotrophic effects on parasympathetic neurons, CNTF was shown to have activities on sympathetic and sensory neurons. It appears not to be involved in motor neuron survival during development and has a trophic influence on degenerating striatal neurons as well as on critical nonstriatal regions. CNTF plays a role in a cardiac signal transduction pathway that regulates obesity-related left ventricular hypertrophy.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
25707
Immunogen:
Rat partial recombinant protein (AA 2-200) was used as the immunogen for this CNTF antibody.
Limitation:
This CNTF antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Mouse, Rat