CRM1 Antibody

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NSJ Bioreagents
Product Code: NSJ-R32412
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R32412-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the CRM1 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

1 / 7
Western blot testing of 1) rat heart, 2) mouse brain, and 3) human A549 lysate with CRM1 antibody. Expected/observed molecular weight ~123 kDa.
2 / 7
IHC testing of FFPE human intestinal cancer tissue with CRM1 antibody. Boil the paraffin sections in pH 6, 10mM citrate buffer for 20 minutes and allow to cool prior to testing.
3 / 7
IHC testing of FFPE mouse intestine with CRM1 antibody. Boil the paraffin sections in pH 6, 10mM citrate buffer for 20 minutes and allow to cool prior to testing.
4 / 7
IHC testing of FFPE rat testis with CRM1 antibody. Boil the paraffin sections in pH 6, 10mM citrate buffer for 20 minutes and allow to cool prior to testing.
5 / 7
IHC testing of frozen mouse intestine tissue with CRM1 antibody.
6 / 7
IHC testing of frozen rat intestine tissue with CRM1 antibody.
7 / 7
IHC testing of frozen rat testis tissue with CRM1 antibody.
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Western blot testing of 1) rat heart, 2) mouse brain, and 3) human A549 lysate with CRM1 antibody. Expected/observed molecular weight ~123 kDa.
IHC testing of FFPE human intestinal cancer tissue with CRM1 antibody. Boil the paraffin sections in pH 6, 10mM citrate buffer for 20 minutes and allow to cool prior to testing.
IHC testing of FFPE mouse intestine with CRM1 antibody. Boil the paraffin sections in pH 6, 10mM citrate buffer for 20 minutes and allow to cool prior to testing.
IHC testing of FFPE rat testis with CRM1 antibody. Boil the paraffin sections in pH 6, 10mM citrate buffer for 20 minutes and allow to cool prior to testing.
IHC testing of frozen mouse intestine tissue with CRM1 antibody.
IHC testing of frozen rat intestine tissue with CRM1 antibody.
IHC testing of frozen rat testis tissue with CRM1 antibody.

Documents

Further Information

Application Details :
Western blot: 0.1-0.5ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunohistochemistry (Frozen): 0.5-1ug/ml
Application Note:
Optimal dilution of the CRM1 antibody should be determined by the researcher.
Description:
Exportin 1 (XPO1), also known as chromosomal maintenance 1 (CRM1), is an eukaryotic protein that mapped to human chromosome 2p16 by fluorescence in situ hybridization. This protein mediates leucine-rich nuclear export signal (NES)-dependent protein transport. It specifically inhibits the nuclear export of Rev and U snRNAs. Additionally, this protein is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. It also regulates NFAT and AP-1.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids N966-D1071 from the human protein were used as the immunogen for the CRM1 antibody.
Limitation:
This CRM1 antibody is available for research use only.
Localization:
Nuclear
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
O14980