CUL1 Antibody

NSJ Bioreagents
Product Code: NSJ-R30634
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R30634-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the CUL1 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

1 / 1
Western blot testing of CUL1 antibody and Lane 1: MM453; 2: HT1080; 3: SMMC-7721; Predicted size: 90 KD; Observed size: 90 KD

Western blot testing of CUL1 antibody and Lane 1: MM453; 2: HT1080; 3: SMMC-7721; Predicted size: 90 KD; Observed size: 90 KD

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the CUL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Cullin 1 is a human protein and gene from cullin family. This protein plays an important role in protein degradation and protein ubiquitination. This is an essential component of the SCF(SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. Human CUL1, but not the other closely related cullins 2, 3, 4A, and 5, selectively interacts with human SKP1.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the N-terminus of human Cullin 1 (RQSMAKSRYMELYTHVYNY) was used as the immunogen for this CUL1 antibody (100% homologous in human, mouse and rat).
Limitation:
This CUL1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
Q13616