CUL4A Antibody

Contact us
NSJ Bioreagents
Product Code: NSJ-RQ4317
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ4317-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
After reconstitution, the CUL4A antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

1 / 2
Western blot testing of human 1) HeLa, 2) COLO-320, 3) MDA-MB-231, 4) Jurkat and 5) PANC-1 cell lysate with CUL4A antibody at 0.5ug/ml. Predicted molecular weight ~88 kDa.
2 / 2
Western blot testing of rat 1) brain, 2) spleen, 3) heart, 4) testis and mouse 5) brain, 6) spleen, 7) heart and 8) testis lysate with CUL4A antibody at 0.5ug/ml. Predicted molecular weight ~88 kDa.
❮❯

Western blot testing of human 1) HeLa, 2) COLO-320, 3) MDA-MB-231, 4) Jurkat and 5) PANC-1 cell lysate with CUL4A antibody at 0.5ug/ml. Predicted molecular weight ~88 kDa.
Western blot testing of rat 1) brain, 2) spleen, 3) heart, 4) testis and mouse 5) brain, 6) spleen, 7) heart and 8) testis lysate with CUL4A antibody at 0.5ug/ml. Predicted molecular weight ~88 kDa.

Documents

Further Information

Application Details :
Western blot: 0.5-1ug/ml, Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the CUL4A antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Description:
Cullin-4A is a protein that in humans is encoded by the CUL4A gene. It belongs to the cullin family of ubiquitin ligase proteins and is highly homologous to the CUL4B protein. CUL4A regulates numerous key processes such as DNA repair, chromatin remodeling, spermatogenesis, haematopoiesis and the mitotic cell cycle. As a result, CUL4A has been implicated in several cancers and the pathogenesis of certain viruses including HIV. Interestingly, a component of a CUL4A complex, Cereblon, was discovered to be a major target of the teratogenic agent thalidomide.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
A recombinant human protein corresponding to amino acids M494-A759 was used as the immunogen for the CUL4A antibody.
Limitation:
This CUL4A antibody is available for research use only.
Purity:
Antigen affinity purified
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
Q13619