CXCL4 Antibody
| Code | Size | Price |
|---|
| NSJ-R30518-100ug | 100 ug | £535.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
After reconstitution, the CXCL4 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
Documents
Further Information
Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting points. Titration of the CXCL4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Chemokine (C-X-C motif) ligand 4, is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. It belongs to the CXC chemokine family. The gene contains 3 exons spanning approximately 1 kb. It is encoded on a 10-kb EcoRI fragment of genomic DNA. By in situ hybridization, the gene is mapped to chromosome 4q12-q21. CXCL4s major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, the cytokine probably has a role in inflammation and wound repair.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids 85-101 (DLQAPLYKKIIKKLLES-human) were used as the immunogen for this CXCL4 antibody.
Limitation:
This CXCL4 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P02776