Cytoglobin Antibody

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NSJ Bioreagents
Product Code: NSJ-R30742
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R30742-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
After reconstitution, the Cytoglobin antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of Cytoglobin antibody and Lane 1: rat brain; 2: (r) small intestine; 3: (r) liver; 4: (r) kidney; 5: human SGC; 6: (h) COLO320; 7: SMMC-7721; 8: PANC; 9: HeLa cell lysate. Predicted/observed molecular weight: ~21kDa.
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Western blot testing of Cytoglobin antibody and Lane 1: rat brain; 2: (r) small intestine; 3: (r) liver; 4: (r) kidney; 5: human SGC; 6: (h) COLO320; 7: SMMC-7721; 8: PANC; 9: HeLa cell lysate. Predicted/observed molecular weight: ~21kDa.

Documents

Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the Cytoglobin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Cytoglobin (CYGB), also called HGB or STAP, is a ubiquitously expressed hexacoordinate hemoglobin that may facilitate diffusion of oxygen through tissues, scavenge nitric oxide or other reactive oxygen species, or serve a protective function during oxidative stress. The CYGB gene contains four exons and spans about 9 kb. Cytoglobin has many elements common to vertebrate globins, including invariant histidine residues, and the amino acids that form the heme pocket share similarity with pentacoordinate myoglobin. In contrast to the high oxygen affinities displayed by most hexacoordinate hemoglobins, the characteristics of CYGB indicate that it can facilitate oxygen transport. Because the oxygen affinity of CYGB is more similar to myoglobin than to neuroglobin, and the oxy form of CYGB resists autooxidation, CYGB is proposed to represent a tissue oxygen reservoir.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the N-terminus of human Cytoglobin (FVNFPSAKQYFSQFKHMED) was used as the immunogen for this Cytoglobin antibody (100% rat homology).
Limitation:
This Cytoglobin antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
Q8WWM9