Desmin Antibody

NSJ Bioreagents
Product Code: NSJ-R30031
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R30031-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG1
Antibody Clonality: Monoclonal
Antibody Clone: DE-U-10, aka DES-82
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rabbit
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the Desmin antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

1 / 2
IHC-P: Desmin antibody testing of rat heart tissue~
2 / 2
Western blot testing of 1) rat skeletal muscle, 2) rat heart, 3) mouse skeletal muscle and 4) mouse heart with Desmin antibody. Predicted molecular weight ~54 kDa.

IHC-P: Desmin antibody testing of rat heart tissue~
Western blot testing of 1) rat skeletal muscle, 2) rat heart, 3) mouse skeletal muscle and 4) mouse heart with Desmin antibody. Predicted molecular weight ~54 kDa.

Further Information

Application Details :
Western blot: 2ug/ml,IHC (Paraffin): 2-4ug/ml
Application Note:
The stated application concentrations are suggested starting points. Titration of the Desmin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Desmin belongs to the type III family of intermediate filaments, a class of cytoskeletal elements. The DES gene encodes a cytoskeletal protein found in smooth, cardiac, and heart muscles. Tidball(1992) found that Desmin was codistributed with actin thin filaments within the cellular processes of myotendinous junctions in frog skeletal muscle. DES gene contains 9 exons and spans about 8.4 kb. By in situ hybridization, Viegas-Pequignot et al.(1989) localized the gene to 2q35. Mutations are responsible for idiopathic dilated cardiomyopathy.
Format :
Ascites
Formulation :
0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS
Gene ID #:
1674
Immunogen:
Desmin from pig stomach was used as the immunogen for this Desmin antibody.
Limitation:
This Desmin antibody is available for research use only.
Purity:
Unpurified ascites
Species Reactivity :
Human, mouse, rat, rabbit