Dopamine Receptor D3 Antibody

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NSJ Bioreagents
Product Code: NSJ-R30661
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R30661-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the Dopamine Receptor D3 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of Dopamine Receptor D3 antibody and Lane 1: rat testis; 2: rat brain; 3: U87; 4: HeLa cell lysate~
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IHC-P: Dopamine Receptor D3 antibody testing of rat brain tissue
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Western blot testing of Dopamine Receptor D3 antibody and Lane 1: rat testis; 2: rat brain; 3: U87; 4: HeLa cell lysate~
IHC-P: Dopamine Receptor D3 antibody testing of rat brain tissue

Documents

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the Dopamine Receptor D3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
DRD3 is a dopamine receptor that differs in its pharmacology and signaling system from the D1 and D2 receptors and represents both an autoreceptor and a postsynaptic receptor. DRD3 is localized to limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. The DRD3 gene, which is mapped to chromosome 3, is like the DRD2 gene but unlike most other members of this superfamily and it contains introns, 5 in number. The position of 2 of the introns corresponds to that of introns in DRD2. The D3 receptor appeared to mediate some of the effects of antipsychotic drugs and drugs used in the treatment of Parkinson disease, which were previously though to interact only with D2 receptors.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of human Dopamine Receptor D3 (NTHCQTCHVSPELYSA) was used as the immunogen for this Dopamine Receptor D3 antibody.
Limitation:
This Dopamine Receptor D3 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
P35462