EGFR Antibody
| Code | Size | Price |
|---|
| NSJ-R31449-100ug | 100 ug | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Rat
Application: Western Blot (WB)
Storage:
After reconstitution, the EGFR antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
Documents
Further Information
Application Details :
Western blot: 0.5-1ug/ml,Immunofluorescence: 2-4ug/ml
Application Note:
The stated application concentrations are suggested starting points. Titration of the EGFR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
The epidermal growth factor receptor (EGFR; ErbB1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. It is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB1), HER2/c-neu (ErbB2), Her 3 (ErbB3) and Her 4 (ErbB4). It exists on the cell surface and is activated by binding of its specific ligands, including epidermal growth factor and transforming growth factor alpha (TGFalpha). EGFR and its ligands are cell signaling molecules involved in diverse cellular functions, including cell proliferation, differentiation, motility, and survival, and in tissue development. Mutations that lead to overexpression or overactivity have been associated with a number of cancers, including lung cancer and glioblastoma multiform.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
1956
Immunogen:
Human partial recombinant protein (AA 25-346) was used as the immunogen for this EGFR antibody.
Limitation:
This EGFR antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human