EIF2B Antibody (EIF2S2)

NSJ Bioreagents
Product Code: NSJ-R31277
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31277-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
After reconstitution, the EIF2B antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of human 1) HepG2, 2) 293T and 3) Raji cell lysate with EIF2B antibody.  Expected molecular weight: ~38 kDa.

Western blot testing of human 1) HepG2, 2) 293T and 3) Raji cell lysate with EIF2B antibody.  Expected molecular weight: ~38 kDa.

Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the EIF2B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Eukaryotic translation initiation factor 2 subunit 2, also called EIF2B, is a protein that in humans is encoded by the EIF2S2 gene. This gene belongs to the EIF-2-beta family. Eukaryotic translation initiation factor 2 (EIF2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF2 complex for another round of initiation.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of human EIF2 beta (FQAVTGKRAQLRAKAN) was used as the immunogen for this EIF2B antibody (100% homologous in human, mouse and rat).
Limitation:
This EIF2B antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
P20042