EphB3 Antibody Ephrin Receptor B3

NSJ Bioreagents
Product Code: NSJ-R30645
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R30645-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the EphB3 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of EphB3 antibody and Lane 1: HeLa; 2: A549 cell lysate~
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IHC-P: EphB3 antibody testing of human lung cancer tissue

Western blot testing of EphB3 antibody and Lane 1: HeLa; 2: A549 cell lysate~
IHC-P: EphB3 antibody testing of human lung cancer tissue

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the EphB3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Ephrin Receptor B3, is also known as human embryo kinase2 (HEK2) or Eph-like tyrosine kinase 2 (ETK2) is a member of the EPH/ELK family of tyrosine kinases. The gene encodes a 998-amino acid polypeptide having a single putative transmembrane domain, a secretory signal sequence, and two fibronectin repeats. The gene is mapped to human chromosome 3q21-qter. EphB3 interacts with two ligands of EPH-related kinases (LERKs), LERK2/EFNB1 and LERK5/EFNB2. Coincubation of EphB3- and LERK2-expressing cells induces cell-cell adhesion and aggregation. Additionally, coexpression of the two proteins results in reduced kinase activity of EphB3.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of human Eph receptor B3 (SIQDMRLQMNQTLPVQV) was used as the immunogen for this EphB3 antibody (100% homologous in human, mouse and rat).
Limitation:
This EphB3 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
P54753