Estrogen Receptor beta Antibody

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NSJ Bioreagents
Product Code: NSJ-R32865
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R32865-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
After reconstitution, the ESR2 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of 1) rat testis, 2) rat ovary, 3) mouse testis, 4) rat ovary, 5) human HeLa, 6) human MCF7, 7) human MDA-MB-231, 8) human MDA-MB-453 and 9) human SK-OV-3 lysate with ESR2 antibody at 0.5ug/ml. Predicted molecular weight: 53~59 kDa.
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Western blot testing of 1) rat testis, 2) rat ovary, 3) mouse testis, 4) rat ovary, 5) human HeLa, 6) human MCF7, 7) human MDA-MB-231, 8) human MDA-MB-453 and 9) human SK-OV-3 lysate with ESR2 antibody at 0.5ug/ml. Predicted molecular weight: 53~59 kDa.

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Further Information

Application Details :
Western Blot: 0.5-1ug/ml
Application Note:
Optimal dilution of the ESR2 antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Description:
Estrogen receptor-beta (ESR2) is a member of the superfamily of nuclear receptors, which can transduce extracellular signals into transcriptional responses. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
A recombinant protein corresponding to amino acids F289-R501 was used as the immunogen for the ESR2 antibody.
Limitation:
This ESR2 antibody is available for research use only.
Localization:
Predominantly nuclear
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
Q92731