Fibrinogen alpha chain Antibody (FGA)

NSJ Bioreagents
Product Code: NSJ-R32595
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R32595-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Rat
Application: Western Blot (WB)
Storage:
After reconstitution, the Fibrinogen alpha chain antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of 1) rat skeletal muscle and 2) human HepG2 cell lysate with Fibrinogen alpha chain antibody at 0.5ug/ml. Predicted molecular weight ~95 kDa (alpha-E isoform).

Western blot testing of 1) rat skeletal muscle and 2) human HepG2 cell lysate with Fibrinogen alpha chain antibody at 0.5ug/ml. Predicted molecular weight ~95 kDa (alpha-E isoform).

Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
Optimal dilution of the Fibrinogen alpha chain antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Description:
Fibrinogen alpha chain is a protein that in humans is encoded by the FGA gene. This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids 687-727 (RTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGSVLRVE-human) were used as the immunogen for the Fibrinogen alpha chain antibody. This sequence is specific to the alpha-E isoform and not found in the alpha isoform.
Limitation:
This Fibrinogen alpha chain antibody is available for research use only.
Localization:
Secreted
Purity:
Antigen affinity
Species Reactivity :
Human, Rat
Species Reactivity (Predicted):
Mouse
Uniprot #:
P02671