Fibrinogen gamma chain Antibody (FGG)

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NSJ Bioreagents
Product Code: NSJ-R32594
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R32594-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the Fibrinogen gamma chain antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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IHC testing of FFPE human liver cancer tissue with Fibrinogen gamma chain antibody at 1ug/ml. HIER: steam section in pH6 citrate buffer for 20 min.
2 / 4
Western blot testing of 1) rat liver, 2) mouse liver and 3) human HepG2 lysate with Fibrinogen gamma chain antibody at 0.5ug/ml. Predicted molecular weight ~50 kDa.
3 / 4
Flow cytometry testing of human A549 cells with Fibrinogen gamma antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Fibrinogen gamma antibody.
4 / 4
Flow cytometry testing of human SiHa cells with Fibrinogen gamma antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Fibrinogen gamma antibody.
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IHC testing of FFPE human liver cancer tissue with Fibrinogen gamma chain antibody at 1ug/ml. HIER: steam section in pH6 citrate buffer for 20 min.
Western blot testing of 1) rat liver, 2) mouse liver and 3) human HepG2 lysate with Fibrinogen gamma chain antibody at 0.5ug/ml. Predicted molecular weight ~50 kDa.
Flow cytometry testing of human A549 cells with Fibrinogen gamma antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Fibrinogen gamma antibody.
Flow cytometry testing of human SiHa cells with Fibrinogen gamma antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Fibrinogen gamma antibody.

Documents

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml,Flow cytometry: 1-3ug/million cells
Application Note:
Optimal dilution of the Fibrinogen gamma chain antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Description:
Fibrinogen gamma chain, also known as FGG, is a human gene found on chromosome 4. The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids 133-163 (IRYLQEIYNSNNQKIVNLKEKVAQLEAQCQE-human) were used as the immunogen for the Fibrinogen gamma chain antibody.
Limitation:
This antibody is available for research use only.
Localization:
Secreted
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
P02679