FosB Antibody

NSJ Bioreagents
Product Code: NSJ-R30550
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R30550-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
After reconstitution, the FosB antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of FosB antibody and Lane 1: HT1080; 2: SW620; 3: HeLa; 4: SMMC-7721; 5: MM453 cell lysate

Western blot testing of FosB antibody and Lane 1: HT1080; 2: SW620; 3: HeLa; 4: SMMC-7721; 5: MM453 cell lysate

Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the FosB antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
FBJ murine osteosarcoma viral oncogene homolog B is a protein that in humans is encoded by the FOSB gene. It is a member of Fos gene family which consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. The proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Delta FOSB is a truncated splice variant of FOSB. It has been implicated in the development of drug addiction and control of the reward system in the brain, and is linked to changes in a number of other gene products such as CREB and sirtuins. It also regulates the commitment of mesenchymal precursor cells to the adipocyte or osteoblast lineage.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the N-terminus of human FosB (MFQAFPGDYDSGSRC) was used as the immunogen for this FosB antibody (100% homologous in human, mouse and rat).
Limitation:
This FosB antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
P53539