FOXM1 Antibody
| Code | Size | Price |
|---|
| NSJ-R31607-100ug | 100 ug | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
After reconstitution, the FOXM1 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
Documents
Further Information
Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the FOXM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Forkhead box protein M1 is encoded by the FOXM1 gene. It is a member of the FOX family of transcription factors. FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases and also in the control of cell proliferation. The gene is now known as a human proto-oncogene. Abnormal upregulation of the protein is involved in the oncogenesis of basal cell carcinoma, the most common human cancer worldwide. It is hypothesized that FOXM1 induces cancer initiation through stem/progenitor cell expansion. Additionally, FOXM1 has been shown to modulate the epigenome. It was found that overexpression of the protein brain washes normal cells to adopt cancer-like epigenome.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
2305
Immunogen:
Human partial recombinant protein (AA 411-763) was used as the immunogen for this FOXM1 antibody.
Limitation:
This FOXM1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human