Gelsolin Antibody

NSJ Bioreagents
Product Code: NSJ-R30038
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R30038-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG1
Antibody Clonality: Monoclonal
Antibody Clone: GS-2C4, aka GEL-42
Regulatory Status: RUO
Target Species:
  • Human
  • Rabbit
Applications:
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the Gelsolin antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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IHC testing of FFPE human lung cancer tissue with Gelsolin antibody. HIER: steamed with pH6 citrate buffer, HRP-staining.~
2 / 2
IHC testing of FFPE human intestinal cancer tissue with Gelsolin antibody. HIER: steamed with pH6 citrate buffer, HRP-staini

IHC testing of FFPE human lung cancer tissue with Gelsolin antibody. HIER: steamed with pH6 citrate buffer, HRP-staining.~
IHC testing of FFPE human intestinal cancer tissue with Gelsolin antibody. HIER: steamed with pH6 citrate buffer, HRP-staini

Further Information

Application Details :
Western blot: 0.5-1ug/ml,IHC (Paraffin): 1-2ug/ml,Immunohistochemistry (Frozen): 1-2ug/ml--formalin or acetone fixed tissues
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the Gelsolin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Gelsolin, a protein of leukocytes, platelets, and other cells, severs actin filaments in the presence of submicromolar calcium, thereby solating cytoplasmic actin gels. A gelsolin variant with 23 more N-terminal amino acids is a plasma component probably involved in the clearance of actin, the most abundant human protein, from the circulation. Gelsolin is located in 9q34. Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain.
Format :
Ascites
Formulation :
0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS
Gene ID #:
2934
Immunogen:
Human plasma gelsolin was used as the immunogen for this Gelsolin antibody.
Limitation:
This Gelsolin antibody is available for research use only.
Purity:
Ascites
Species Reactivity :
Human, rabbit