GPR30 Antibody
| Code | Size | Price |
|---|
| NSJ-R31359-100ug | 100 ug | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Monkey
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
After reconstitution, the GPR30 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
Documents
Further Information
Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the GPR30 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
G-protein coupled estrogen receptor 1 (GPER1), also known as the GPR30 or CEPR, is a G protein-coupled receptor that in humans is encode d by the GPER gene. This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. GPR30 therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of human G-protein coupled receptor 30 (ENVFISVHLLQRTQ) was used as the immunogen for this GPR30 antibody.
Limitation:
This GPR30 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Monkey
Uniprot #:
Q99527