HYAL1 Antibody

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NSJ Bioreagents
Product Code: NSJ-R31302
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31302-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunocytochemistry (ICC)
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the HYAL1 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of 1) human HepG2, 2) human PC-3, 3) monkey COS-7, 4) rat liver, 5) mouse liver and 6) mouse kidney tissue lysate with HYAL1 antibody. Expected molecular weight: 48-60 kDa.
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IHC-P: HYAL1 antibody testing of human intestine cancer tissue
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IHC-F testing of HYAL1 antibody and human placenta tissue
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ICC testing of HYAL1 antibody and MCF-7 cells
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Western blot testing of 1) human HepG2, 2) human PC-3, 3) monkey COS-7, 4) rat liver, 5) mouse liver and 6) mouse kidney tissue lysate with HYAL1 antibody. Expected molecular weight: 48-60 kDa.
IHC-P: HYAL1 antibody testing of human intestine cancer tissue
IHC-F testing of HYAL1 antibody and human placenta tissue
ICC testing of HYAL1 antibody and MCF-7 cells

Documents

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunohistochemistry (Frozen): 0.5-1ug/ml,Immunocytochemistry: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the HYAL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Hyaluronidase-1, also known as LUCA1, is an enzyme that in humans is encoded by the HYAL1 gene. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is though to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the N-terminus of human Hyaluronidase-1 (FTTVWNANTQWCLERH) was used as the immunogen for this HYAL1 antibody.
Limitation:
This HYAL1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
Q12794