HYAL1 Antibody

NSJ Bioreagents
Product Code: NSJ-R31303
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31303-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
After reconstitution, the HYAL1 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of HYAL1 antibody and Lane 1: rat NRK; 2: mouse liver; 3: (m) kidney; 4: (m) SP2/0 cell lysate

Western blot testing of HYAL1 antibody and Lane 1: rat NRK; 2: mouse liver; 3: (m) kidney; 4: (m) SP2/0 cell lysate

Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the HYAL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Hyaluronidase-1, also known as LUCA1, is an enzyme that in humans is encoded by the HYAL1 gene. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is though to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of mouse Hyaluronidase-1 (LKDRAQMAMKFRCRCYR) was used as the immunogen for this HYAL1 antibody.
Limitation:
This HYAL1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Mouse
Uniprot #:
Q91ZJ9