HYAL3 Antibody

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NSJ Bioreagents
Product Code: NSJ-R30955
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R30955-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the HYAL3 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of HYAL3 antibody and Lane 1: 22RV; 2: HeLa; 3: V20S cell lysate. Expected size: ~47KD~
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IHC-P: HYAL3 antibody testing of human breast cancer tissue
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Western blot testing of HYAL3 antibody and Lane 1: 22RV; 2: HeLa; 3: V20S cell lysate. Expected size: ~47KD~
IHC-P: HYAL3 antibody testing of human breast cancer tissue

Documents

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the HYAL3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Hyaluronoglucosaminidase 3 is anenzyme that in humans is encoded by the HYAL3 gene, also known as LUCA3, Hyaluronidase-3, Lung carcinoma protein 3, LUCA-3, LUCA14, and Minna14. By Northern blot analysis, expression of a 2.1-kb transcript that was strongest in testis and bone marrow, but relatively weak in other organs. HYAL3 encodes a predicted 417-amino acid protein. This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is though to be involved in cell proliferation, migration and differentiation. However, this protein has not yet been shown to have hyaluronidase activity. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of human Hyaluronoglucosaminidase 3 (SHQRCHGHGRCARRD) was used as the immunogen for this HYAL3 antibody.
Limitation:
This HYAL3 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse
Uniprot #:
O43820