I12 p40 / Il-12b Antibody

NSJ Bioreagents
Product Code: NSJ-R32887
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R32887-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the Il12 p40 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of rat kidney tissue with Il12 p40 antibody at 0.5ug/ml. Predicted molecular weight 37-40 kDa.~
2 / 2
IHC testing of FFPE rat spleen tissue with Il12 p40 antibody at 1ug/ml. Required HIER: steam section in pH6 citrate buffer for 20

Western blot testing of rat kidney tissue with Il12 p40 antibody at 0.5ug/ml. Predicted molecular weight 37-40 kDa.~
IHC testing of FFPE rat spleen tissue with Il12 p40 antibody at 1ug/ml. Required HIER: steam section in pH6 citrate buffer for 20

Further Information

Application Details :
Western Blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml,Direct ELISA (recombinant rat protein): 0.1-0.5ug/ml (BSA-free format available)
Application Note:
Optimal dilution of the Il12 p40 antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Description:
Subunit beta of interleukin 12 (IL12B), also known as interleukin 12B, or interleukin-12 subunit p40, is a subunit of human interleukin 12. It is mapped to 5q33.3. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
A recombinant rat protein corresponding to amino acids M23-E250 was used as the immunogen for the Il12 p40 antibody.
Limitation:
This Il12 p40 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Rat
Uniprot #:
E9PU71