ICAM-1 Antibody

NSJ Bioreagents
Product Code: NSJ-R31437
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31437-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
The lyophilized ICAM-1 antibody can be stored at 40. After reconstitution, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of ICAM-1 antibody and human samples 1: HEPG2; 2: K562; 3: A549; 4: HT1080 lysate. The glycoprotein is routinely visualized at 75~115KD.
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IHC-P: ICAM-1 antibody testing of human intestine cancer tissue
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IHC-P: ICAM-1 antibody testing of human lung cancer tissue

Western blot testing of ICAM-1 antibody and human samples 1: HEPG2; 2: K562; 3: A549; 4: HT1080 lysate. The glycoprotein is routinely visualized at 75~115KD.
IHC-P: ICAM-1 antibody testing of human intestine cancer tissue
IHC-P: ICAM-1 antibody testing of human lung cancer tissue

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting points. Titration of the ICAM-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Intercellular adhesion molecule-1 is an integral membrane protein, a member of the immunoglobulin superfamily, and a ligand for lymphocyte function-associated (LFA) antigens, a beta 2 leukocyte integrin. The normal function of human ICAM-1 is to provide adhesion between endothelial cells and leukocytes after injury or stress. ICAM-1 binds to leukocyte function-associated antigen (LFA-1) or macrophage-1 antigen (Mac-1). It is found on leukocytes, fibroblasts, epithelial cells and endothelial cells and its expression is regulated by inflammatory cytokines. ICAM-1 has a tissue distribution similar to that of the major histocompatibility complex class II antigens and is likely to play a role in inflammatory responses.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Human partial recombinant protein (amino acids 28-480) was used as the immunogen for this ICAM-1 antibody.
Limitation:
This ICAM-1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P05362