IKKb Antibody
| Code | Size | Price |
|---|
| NSJ-R31146-100ug | 100 ug | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
After reconstitution, the IKKb antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
Documents
Further Information
Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the IKKb antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
IKBKB (Inhibitor of Kappa Light Chain Gene Enhancer in B Cells, Kinase of, Beta), also known as IKKb, NFKBIKB, and IKK2, is a protein that in humans is encoded by the IKBKB gene. Shindo et al.(1998) mapped the gene to chromosome 8p12-p11 by FISH. Mercurio et al.(1997) found that mutations in IKK2/IKKb had a more pronounced effect upon NFKB activation than did comparable mutations in IKK1/IKKa. Yin et al.(1998) tested the activity of various antiinflammatory agents on the IKK complex. They demonstrated that aspirin and sodium salicylate specifically inhibit IKK beta activity in vitro and in vivo by binding to IKK beta to reduce ATP binding.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of human IKK beta (QEMVRLLLQAIQSFEKK) was used as the immunogen for this IKKb antibody (100% mouse homology).
Limitation:
This IKKb antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
O14920