IL-17F Antibody

NSJ Bioreagents
Product Code: NSJ-R32917
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R32917-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Rat
Application: Western Blot (WB)
Storage:
After reconstitution, the IL-17F antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of rat PC-12 cell lysate with IL-17F antibody at 0.5ug/ml. Predicted molecular weight: ~15 kDa (unmodified monomer), 15-20 kDa (glycosylated monomer), ~30 kDa (homodimer) and 30~40 kDa (glycosylated homodimer).

Western blot testing of rat PC-12 cell lysate with IL-17F antibody at 0.5ug/ml. Predicted molecular weight: ~15 kDa (unmodified monomer), 15-20 kDa (glycosylated monomer), ~30 kDa (homodimer) and 30~40 kDa (glycosylated homodimer).

Further Information

Application Details :
Western Blot: 0.5-1ug/ml,Direct ELISA (recombinant human proteion): 0.1-0.5ug/ml (BSA-free format available)
Application Note:
Optimal dilution of the IL-17F antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Description:
Interleukin 17F, also called IL17F is involved in the regulation of normal versus aberrant T-cell responses. This gene is mapped to 6p12.2. The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. It is suggested that targeting IL17 and IL17F or antagonizing IL17R might mitigate neutrophil-mediated inflammation in CF.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
A recombinant human protein corresponding to amino acids R31-Q163 was used as the immunogen for the IL-17F antibody.
Limitation:
This IL-17F antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Rat
Uniprot #:
Q96PD4