IL1RA Antibody / Interleukin-1 Receptor Antagonist

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NSJ Bioreagents
Product Code: NSJ-R32852
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R32852-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
After reconstitution, the IL1RA antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of human 1) HeLa, 2) COLO320, 3) HepG2, 4) Jurkat, 5) K562, 6) HT1080, 7) U-2-OS and 8) PANC-1 cell lysate with IL1RA antibody at 0.5ug/ml. Predicted molecular weight ~20 kDa.~
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Western blot testing of human 1) RT4 and 2) HaCaT
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Western blot testing of human 1) HeLa, 2) COLO320, 3) HepG2, 4) Jurkat, 5) K562, 6) HT1080, 7) U-2-OS and 8) PANC-1 cell lysate with IL1RA antibody at 0.5ug/ml. Predicted molecular weight ~20 kDa.~
Western blot testing of human 1) RT4 and 2) HaCaT

Documents

Further Information

Application Details :
Western Blot: 0.5-1ug/ml,ELISA (human recombinant protein): 0.1-0.5ug/ml (BSA-free format available)
Application Note:
Optimal dilution of the IL1RA antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Description:
The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
A recombinant protein corresponding to amino acids R26-E177 was used as the immunogen for the IL1RA antibody.
Limitation:
This IL1RA antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P18510