IL-2 Receptor Antibody (beta subunit)
| Code | Size | Price |
|---|
| NSJ-R30696-100ug | 100 ug | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
After reconstitution, the IL-2 Receptor antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
Documents
Further Information
Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the IL-2 Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Interleukin 2 receptor beta, also called CD122, is a protein that in humans is encoded by the IL2RB gene. The gene represents the beta subunit and is a type I membrane protein. The IL2RB gene contains 10 exons spanning about 24.3 kb and that the gene product is encoded by exons 2-10. IL-2 receptor is present in three forms with respect to binding ability to IL-2: high, intermediate, and low affinity forms. Analysis of mutants of the beta chain of the IL-2 receptor reveals that the granulocyte and monocyte differentiation signals are triggered by different cytoplasmic domains, showing that the signaling pathways responsible for these unique developmental outcomes are separable.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids 117-135 (RVMAIQDFKPFENLRLMAP-human) of the beta subunit were used as the immunogen for this IL-2 Receptor antibody.
Limitation:
This IL-2 Receptor antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P14784