IL-2 Receptor Antibody (beta subunit)

NSJ Bioreagents
Product Code: NSJ-R31980
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31980-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
After reconstitution, the IL2RB antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

1 / 1
Western blot testing of mouse 1) lung, 2) spleen, 3) testis lysate with IL2RB antibody. Expected molecular weight ~61 kDa (unmodified), 70-75 kDa (glycosylated).

Western blot testing of mouse 1) lung, 2) spleen, 3) testis lysate with IL2RB antibody. Expected molecular weight ~61 kDa (unmodified), 70-75 kDa (glycosylated).

Further Information

Application Details :
Western blot: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the IL2RB antibody should be determined by the researcher.
Description:
IL2RB (INTERLEUKIN 2 RECEPTOR, BETA), also called CD122, is a protein that in humans is encoded by the IL2RB gene. The gene represents the beta subunit and is a type I membrane protein. IL2RB is mapped to 22q12.3. The IL2RB gene contains 10 exons spanning about 24.3 kb and that the gene product is encoded by exons 2-10. The IL2 receptor is present in 3 forms with respect to binding ability to IL2: high, intermediate, and low affinity forms. Analysis of mutants of the beta chain of the IL2 receptor reveals that the granulocyte and monocyte differentiation signals are triggered by different cytoplasmic domains, showing that the signaling pathways responsible for these unique developmental outcomes are separable.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids NLHGQDQDRGQGPILTLNTDAYLSLQELQAQDSVHLI of mouse IL2RB were used as the immunogen for the IL2RB antibody.
Limitation:
This IL2RB antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Mouse
Uniprot #:
P16297