IL2RA Antibody

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NSJ Bioreagents
Product Code: NSJ-R30839
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R30839-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the IL2RA antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of IL2RA antibody and Lane 1: SMMC-7721; 2: A549; 3: Jurkat; 4: MCF-7; 5: Raji; 6: PANC; Predicted size: 25~45KD depending on level of glycosylation
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Western blot testing of IL2RA antibody and Lane 1: SMMC-7721; 2: A549; 3: Jurkat; 4: MCF-7; 5: Raji; 6: PANC; Predicted size: 25~45KD depending on level of glycosylation

Documents

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the IL2RA antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Interleukin 2 receptor, alpha, also called IL2R, IL2R, Alpha Chain or CD25, is a protein that in humans is encoded by the IL2RA gene. IL2RA is composed of strand-swapped sushi-like domains, unlike the classical cytokine receptor fold. As a result of this domain swap, it uses a composite surface to dock into a groove on IL2 that also serves as a binding site for antagonist drugs. Homodimeric alpha chains result in low-affinity receptor, while homodimeric beta chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Infection by the protozoan Trypanosoma cruzi causes Chagas disease, characterized by a reduction in the amount of IL2RA expressed on the surface of immune cells. This leads to chronic immune suppression, becoming increasingly severe over the course of many years and ultimately resulting in death if left untreated.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the N-terminus of human IL2RA (MAYKEGTMLNCECKRGFRR) was used as the immunogen for this IL2RA antibody.
Limitation:
This IL2RA antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P01589