INDOL1 Antibody

NSJ Bioreagents
Product Code: NSJ-R30692
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R30692-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
After reconstitution, the INDOL1 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of INDOL1 antibody and Lane 1: A549; 2: human placenta; 3: A431 cell lysate. Expected size: ~45KD

Western blot testing of INDOL1 antibody and Lane 1: A549; 2: human placenta; 3: A431 cell lysate. Expected size: ~45KD

Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the INDOL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
IDO2 (Indoleamine 2,3-dioxygenase 2), also called Indoleamine 2,3-dioxygenase-like 1, is an enzyme encoded by the INDOL1 gene which metabolizes tryptophan in the kynurenine pathway. By genomic sequence analysis, the gene is mapped on chromosome 8p12 just downstream of the INDO gene. And its exact cytogenetic location is 8p11.21. By database analysis using INDO as probe, followed by RT-PCR of total RNA from various tissues, IDO2 is cloned by human and mouse INDOL1. INDOL1 catabolizes tryptophan as determined by Kyn production, but unlike INDO, is inhibited by D-1-methyl-tryptophan(D-1MT) but not the L-1MT stereoisomer.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids 1-20 (MLHFHYYDTSNKIMEPHRPN-human) were used as the immunogen for this INDOL1 antibody.
Limitation:
This INDOL1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
Q6ZQW0